An international research team led by the Hong Kong University of Science and Technology (HKUST) has reportedly developed a groundbreaking blood test for the early detection of Alzheimer’s disease (AD) and mild cognitive impairment (MCI) with remarkable accuracy rates.
The test has recorded accuracy rates of over 96% for AD and 87% for MCI. According to the researchers, this surpasses the performance of existing tests for AD that use amyloid beta (Aβ) 42/40, neurofilament light chain (NfL) or phosphorylated-tau181 (p-tau181) biomarkers.
Potential universal application: Conducted on individuals of Chinese and European descent, the test demonstrates applicability across diverse ethnic groups.
She added, “Our test can also be used to screen suitable individuals for specific drug treatments in clinical studies, and closely monitor disease progression and drug responses. In the future, it may also facilitate the development of personalized treatments, by shedding light on the molecular underpinnings of AD that vary from person to person and between ethnicities.”
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